Gen2 printing - inconsistent errors

Hello, 

Wonder if anyone else is having some errors with the new printing service/Pro layouts…
We're currently using gen1 printing and are trying to move to gen2.  I created new layouts in the Pro Designer (print studio) starting with the default templates offered and editing from there.  We seemed to have some issues trying to convert the legacy layouts so I started from scratch.
I get the print service updated and layouts into the dev studio web designer with no problem. But it seems that almost every other print job fails.  One fails because of our cached service, I found that having the DPI to 96 and toggling off the "Update Map View to Print Scale"  seems to resolve this (I understand the limitation with cached services) but I'm wondering how I'll effectively announce these limitations to our end users.  Will I be able to default the advanced print settings to this?  
I'm also randomly getting error messages stating that the layout item isn't found (even though I just exported out a map with that particular layout template).  Wondering if that is a timeout/login error with AGO?

I know we have some time with this and we are also in the process of trying to retire cached services, but wanted to post and see if anyone else was experiencing any of these issues and if there are workarounds or maybe something on my end I can fix

Mary